INDIANAPOLIS -- The Colts victory over Peyton Manning came at a hefty price. Ben Heller Jersey . Andrew Luck lost his favourite target and the Indianapolis locker room lost one of its most revered leaders when Reggie Wayne was diagnosed Monday with a torn anterior cruciate ligament in his right knee that will cost him the rest of the season. News of Waynes injury hit hard at the team complex. Second-year receiver T.Y. Hilton expressed sadness about losing his mentor. Coach Chuck Pagano tried to lean on his standard line about replacing injured players, though it didnt come with quite the same passion, and Luck blamed himself for putting Wayne in harms way with a low, underthrown ball late in the game against Denver. "Looking back it again today, there was really no one within 30 yards of him. He probably would have scored if I actually give him a decent ball. I feel somewhat responsible for the whole thing," Luck said. "I think I feel sick to my stomach about it a little bit." Wayne, who was not hit on the play, immediately clutched his right knee and stayed on the ground for several minutes as Luck, longtime friend Antoine Bethea, other teammates and a group of trainers gathered around. After making the short walk to the Colts sideline, the man who had played in 189 consecutive games limped into the locker room with tears in his eyes knowing that his season was likely over. Pagano and teammates were hoping for the best. Instead, they got the worst possible news, and theres no doubt Waynes absence will hurt the AFC South leaders. The perennial Pro Bowler leads his team with 38 catches and 503 yards this season. In 13 seasons, all with the Colts, he has 1,006 receptions, 13,506 yards and 80 TD catches -- second in each category on the franchises career charts, behind only ex-teammate Marvin Harrison and ahead of Hall of Famer Raymond Berry. But Waynes impact cant be measured merely by stats. When the Colts (5-2) decided to cut ties with more than a half-dozen high-priced veterans, including Manning, following Indys dismal 2-14 season, Wayne was one of the few holdovers who decided to stick around and rebuild. He even took less money to stay in his adopted hometown, and quickly emerged as a centerpiece of the Colts incredible turnaround. He always plays with passion, which was never more evident than last October against Green Bay. In Indys first game after Pagano was diagnosed with leukemia, Wayne caught 13 passes for 212 yards and almost single-handedly willed the Colts from a 17-3 deficit to a 30-27 victory that ended with Waynes orange gloves, a tribute to Pagano, barely crossing the goal line with 35 seconds to go. Its one of the reasons Pagano believes Wayne will return next season at full throttle. "Hes not going out like this. Hes not going to leave this game like this. Theres no way," said Pagano, who first met Wayne when they were working together at the University of Miami. "Hell fight, hell get his surgery, and hell rehab and hell grind like nobodys ever grinded. Hell do whatever it takes to get back on that football field -- even if its to catch one more pass, make one more block, do one more thing to help this organization win a football game, hell do it. But hes not going out like this." Pagano did not say when Wayne would have surgery though it takes most athletes a year to come back. Some require 18 to 24 months, though Vikings running back Adrian Peterson and former Steelers cornerback Rod Woodson did it quicker than that. Peterson came back in nine months and went on to win last seasons MVP Award. The then-30-year-old Woodson returned to play in the Super Bowl following the 1995 season after tearing up his knee in that seasons opener. Obstacles can be more difficult for older athletes such as Wayne, who turns 35 next month and will be heading into the final year of his contract next season. "There is a thought that the recovery process might be a little slower in athletes as they get older, but there arent any real studies that show its harder to recover," said Dr. David Geier, an orthopedic surgeon and sports medicine specialist in Charleston, S.C. "We think being a high-level athlete in good shape can help because we know that the strength of the muscle going in plays a role how fast you get back. But being a higher level athlete, also means you have a higher bar to achieve to getting back." The Colts have seen this scenario before. In 2007, the then 35-year-old Harrison injured his knee while making a block when another player rolled up on the back of his leg. He missed most of that season and was never the same. He finished 2008 with 60 catches for 636 yards and five TDs but never played another down in the NFL after that season. Pagano doesnt believe it will happen to Wayne. "You just look in the mans eye. When he tells you hes going to do something, I can just look in his eye," Pagano said. "Again, Ive known him for a long time and watched him work over the years and he says Ill be back, I trust hell be back." Since dealing with a high ankle sprain and a sprained knee, which cost him three games as a rookie in 2001, Wayne had not missed a game. That streak that will officially end Nov. 3 at Houston when the Colts return from their bye week. Pagano would not say if the Colts will shop for another replacement. For now, they plan to go with the receivers already on the roster -- Hilton, Darrius Heyward-Bey, LaVon Brazill and David Reed -- and perhaps activate one or both of the teams practice squad, DaRick Rogers or Griff Whalen. Losing Wayne hurts even more because of what has already happened to Indys offence. Starting tight end Dwayne Allen (hip), Indys top two running backs, Vick Ballard (knee) and Ahmad Bradshaw (neck), and starting left guard Donald Thomas (quad) are already on season-ending injured reserve. Wayne is likely to join that list soon. "The first thing out of his mouth is he feels like he let his teammates down because he cant be there now. Thats how unselfish this guy is," Pagano said. "Like I told you, he could give a hoot about the numbers, all that stuff. He just wants to play and help us win a championship. Thats what hes dealing with right now." Bernie Williams Jersey .com) - Ryan Miller made 28 saves to record his fifth shutout of the season and second in as many nights as the Vancouver Canucks defeated the Carolina Hurricanes 3-0 on Friday. Aaron Hicks Jersey . Karlovic of Croatia used his big serve to beat Jiri Vesely of the Czech Republic 7-6 (6), 7-6 (7). Kohlschreiber had lost all of his three previous matches against Istomin but the German broke serve for a decisive 3-2 lead in the third set and held on to reach his first final of the year. https://www.cheapyankees.com/661g-jacoby-ellsbury-jersey-yankees.html . Team officials did not indicate the extent of the injury Saturday, simply listing Rose with "left knee soreness." Rose has played two preseason games without any sign of problems. The first NBA game in South America now will be missing its biggest star.CHARLOTTE, N.C. - Panthers coach Ron Rivera expects to use a running back-by-committee approach against the Chicago Bears on Sunday.With starter DeAngelo Williams out with a sprained ankle and Jonathan Stewart doubtful with a sprained knee, Rivera said Friday that Fozzy Whittaker, Darrin Reaves and recently signed Chris Ogbonnaya will split carries.Rivera said Whittaker and Reaves will get the majority of carries, but hell gravitate toward using the back with the hot hand.It really depends on who looks the best early on, Rivera said. Each guy is going to get some carries early. ... It Fozzy starts having one of those games like he did against Kansas City or Pittsburgh (in the preseason) that could be exciting for him, and for us.Whittaker combined for 162 yards and two touchdowns in those two games and led the Panthers in rushing in the preseason.Mike Tolbert and Richie Brockel will not play, leaving the Panthers without a true fullback.The Panthers didnt sign a replacement free agent fullback this week. Rivera said tight end Brandon Williams and Ed Dickson could see action at that spot. However, Dicksons status for Sunday is up in the air. Rivera said he will make a game-time decision on Dickson (hip).Rivera said Stewart worked very well on the side, but isnt quite ready for game action.He took a big step, Riverra said. Raul Mondesi Yankees Jersey. Williams, the franchises all-time leading rusher, will miss the next two games and possibly more. He tweeted a picture of himself earlier this week wearing a pink cast on his ankle.The Panthers (2-2) enter the game ranked 29th in the league in offence and averaging just 3.1 yards per carry, one of the main reasons for their current two-game losing streak.Quarterback Cam Newton has been a non-factor in the running game. One of the leagues most dangerous quarterbacks with his feet the past three seasons, Newton has only eight carries for 33 yards in three starts.Well see how he feels, Rivera said. Thats what is all based upon, how he looks and how hes feeling more so than anything else. We really havent had an opportunity to put the girth of his plays in for him. So well see. It will depend on how hes feeling.Defensive end Charles Johnson returned to work Friday after missing two days of practice with a hip injury and is probable for Sunday.The Panthers can ill afford to lose Johnson, particularly with Greg Hardy out indefinitely while dealing with the fallout from a domestic violence conviction and Frank Alexander suspended an additional 10 games this week for a second violation of the leagues substance abuse policy.___AP NFL website: www.pro32.ap.org and www.twitter.com/AP_NFL ' ' '